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Rosetta Biosoftware rat onearray plus microarray
Predicting target proteins for CQCQD to attenuate pulmonary albumin leakage based on the analyses of rats pulmonary tissue <t>microarray</t> and also the construction of PPI network. (a) The proteins, encoded by these prioritized hub nodes including Fos, Pik3r1, and Src, were predicted as the key target proteins (red nodes = upregulated DEGs, green nodes = downregulated DEGs, grey nodes = other interactive genes; the size of nodes = the betweenness of the node). (b) The expressions of these 3 prioritized hub nodes in each sample within each group (red represents upregulation and green represents downregulation).
Rat Onearray Plus Microarray, supplied by Rosetta Biosoftware, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Predicting target proteins for CQCQD to attenuate pulmonary albumin leakage based on the analyses of rats pulmonary tissue microarray and also the construction of PPI network. (a) The proteins, encoded by these prioritized hub nodes including Fos, Pik3r1, and Src, were predicted as the key target proteins (red nodes = upregulated DEGs, green nodes = downregulated DEGs, grey nodes = other interactive genes; the size of nodes = the betweenness of the node). (b) The expressions of these 3 prioritized hub nodes in each sample within each group (red represents upregulation and green represents downregulation).

Journal: Evidence-based Complementary and Alternative Medicine : eCAM

Article Title: Key Molecular Mechanisms of Chaiqinchengqi Decoction in Alleviating the Pulmonary Albumin Leakage Caused by Endotoxemia in Severe Acute Pancreatitis Rats

doi: 10.1155/2016/3265368

Figure Lengend Snippet: Predicting target proteins for CQCQD to attenuate pulmonary albumin leakage based on the analyses of rats pulmonary tissue microarray and also the construction of PPI network. (a) The proteins, encoded by these prioritized hub nodes including Fos, Pik3r1, and Src, were predicted as the key target proteins (red nodes = upregulated DEGs, green nodes = downregulated DEGs, grey nodes = other interactive genes; the size of nodes = the betweenness of the node). (b) The expressions of these 3 prioritized hub nodes in each sample within each group (red represents upregulation and green represents downregulation).

Article Snippet: According to the Rosetta Biosoftware, out of 20715 gene probes on the Rat OneArray Plus Microarray, 3190 gens (1678 genes upregulated and 1512 genes downregulated) in S/N DEGs cluster and 4138 genes (2404 genes upregulated and 1734 genes downregulated) in C/S DEGs cluster were differentially expressed ( P < 0.05, |log 2(Ratio)|≧0.585).

Techniques: Microarray